| Barbicambarus cornutus Faxon, 1884 | Bottle brush crayfish |
| Cambarus (Cambarus) bartonii Fabricius, 1798 | Appalachian brook crayfish |
| Cambarus (Cambarus) davidi J. E. Cooper, 2000 | Carolina ladle crayfish |
| Cambarus (Depressicambarus) graysoni Faxon, 1914 | Two-spot crayfish |
| Cambarus (Depressicambarus) latimanus Le Conte, 1856 | Variable Crayfish |
| Cambarus (Depressicambarus) reduncus Hobbs, 1956 | Sickle Crayfish |
| Cambarus (Depressicambarus) sphenoides Hobbs, 1968 | Triangleclaw Crayfish |
| Cambarus (Depressicambarus) striatus Hay, 1902 | Ambiguous Crayfish |
| Cambarus (Depressicambarus) strigosus Hobbs, 1981 | Lean Crayfish |
| Cambarus (Erebicambarus) tenebrosus Hay, 1902 | Cavespring crayfish |
| Cambarus (Hiaticambarus) longirostris Faxon, 1885 | Longnose Crayfish |
| Cambarus (Hiaticambarus) longulus Girard, 1852 | Atlantic Slope Crayfish |
| Cambarus (Jugicambarus) carolinus Erichson, 1846 | Red Burrowing Crayfish |
| Cambarus (Jugicambarus) distans Rhoades, 1944 | Boxclaw crawfish |
| Cambarus (Jugicambarus) dubius Faxon, 1884 | Upland burrowing crayfish |
| Cambarus (Lacunicambarus) diogenes Girard, 1852 | Chimney crayfish |
| Cambarus (Puncticambarus) acuminatus Faxon, 1884 | Acuminate Crayfish |
| Cambarus (Puncticambarus) robustus Girard, 1852 | Big water crayfish |
| Cambarus appalachiensis Loughman, We..., 2017 | Conhaway Crayfish |
| Cambarus catogius | |
| Cambarus jordani Faxon, 1884 | |
| Distocambarus (Distocambarus) devexus Hobbs, 1981 | Broad River Burrowing Crayfish |
| Fallicambarus (Creaserinus) fodiens Cottle, 1863 | Digger crayfish |
| Fallicambarus (Creaserinus) oryktes Penn & Marlow, 1959 | Flatwoods Digger |
| Fallicambarus (Creaserinus) uhleri Faxon, 1884 | |
| Orconectes (Buannulifictus) hobbsi Penn, 1950 | Pontchartrain Painted Crawfish |
| Orconectes (Crockerinus) obscurus Hagen, 1870 | Allegheny crayfish |
| Orconectes (Crockerinus) propinquus Girard, 1852 | Northern clearwater crayfish |
| Orconectes (Crockerinus) rafinesquei Rhoades, 1944 | Rafinesque crayfish |
| Orconectes (Crockerinus) shoupi Hobbs, 1948 | Nashville crayfish |
| Orconectes (Faxonius) limosus Rafinesque, 1817 | Delcore Crayfish |
| Orconectes (Gremicambarus) causeyi Jester, 1967 | Western plains crayfish |
| Orconectes (Gremicambarus) compressus Faxon, 1884 | Slender crayfish |
| Orconectes (Gremicambarus) nais Faxon, 1885 | Water nymph crayfish |
| Orconectes (Gremicambarus) virilis Hagen, 1870 | Common Crawfish |
| Orconectes (Procericambarus) barrenensis Rhoades, 1944 | Barren River crayfish |
| Orconectes (Procericambarus) carolinensis J. E. Cooper..., 1995 | North Carolina crayfish |
| Orconectes (Procericambarus) cristavarius Taylor, 2000 | Spiny stream crayfish |
| Orconectes (Procericambarus) forceps Faxon, 1884 | Surgeon crayfish |
| Orconectes (Procericambarus) hylas Faxon, 1890 | Woodland crayfish |
| Orconectes (Procericambarus) juvenilis Hagen, 1870 | Kentucky River crayfish |
| Orconectes (Procericambarus) placidus Hagen, 1870 | Bigclaw crayfish |
| Orconectes (Procericambarus) punctimanus Creaser, 1933 | Spothand crayfish |
| Orconectes (Procericambarus) putnami Faxon, 1884 | Phallic crayfish |
| Orconectes (Procericambarus) rusticus Girard, 1852 | Rusty crayfish |
| Orconectes (Procericambarus) spinosus Bundy, 1877 | Coona River spiny crayfish |
| Orconectes (Trisellescens) immunis Hagen, 1870 | Calico crayfish |
| Procambarus (Girardiella) gracilis Bundy, 1876 | Prairie crayfish |
| Procambarus (Hagenides) advena LeConte, 1856 | Vidalia Crayfish |
| Procambarus (Hagenides) pygmaeus Hobbs, 1942 | Christmas tree crayfish |
| Procambarus (Leconticambarus) barbatus Faxon, 1890 | Wandering Crayfish |
| Procambarus (Ortmannicus) acutus Girard, 1852 | White river crawfish |
| Procambarus (Ortmannicus) ancylus Hobbs, 1958 | Coastal Plain Crayfish |
| Procambarus (Ortmannicus) blandingii Harlan, 1830 | Santee Crayfish |
| Procambarus (Ortmannicus) enoplosternum Hobbs, 1947 | Black Mottled Crayfish |
| Procambarus (Ortmannicus) fallax Hagen, 1870 | Deceitful Crayfish |
| Procambarus (Ortmannicus) hayi Faxon, 1884 | Straightedge Crayfish |
| Procambarus (Ortmannicus) hybus Hobbs & Walton, 1957 | Smoothnose Crayfish |
| Procambarus (Ortmannicus) leonensis Hobbs, 1942 | Blacknose Crayfish |
| Procambarus (Ortmannicus) litosternum Hobbs, 1947 | Blackwater Crayfish |
| Procambarus (Ortmannicus) pearsei Creaser, 1934 | Carolina Sandhills Crayfish |
| Procambarus (Ortmannicus) seminolae Hobbs, 1942 | Seminole crayfish |
| Procambarus (Pennides) raneyi Hobbs, 1953 | Disjunct Crayfish |
| Procambarus (Pennides) spiculifer LeConte, 1856 | White Tubercled Crayfish |
| Procambarus (Scapulicambarus) clarkii Girard, 1852 | American crayfish |
| Procambarus (Scapulicambarus) paeninsulanus Faxon, 1914 | Peninsula Crayfish |
| Procambarus (Scapulicambarus) troglodytes LeConte, 1856 | Eastern Red Swamp Crawfish |
