| Genus | Acantholespesia
Wood, 1987
| 3 | Species |
| Genus | Afrophylax
Cerretti & O’Hara, 2016
| 1 | Species |
| Genus | Alsomyia
Brauer & von Bergenstamm, 1891
| 11 | Species |
| Genus | Amelibaea
Brauer & von Bergenstamm, 1891
| 2 | Species |
| Genus | Ametadoria
Townsend, 1927
| 10 | Species |
| Genus | Aplomya
Robineau-Desvoidy, 1830
| 48 | Species |
| Genus | Aplomyopsis
Townsend, 1927
| 2 | Species |
| Genus | Aprotheca
Macquart, 1851
| 2 | Species |
| Genus | Austronilea
Crosskey, 1967
| 1 | Species |
| Genus | Austrophryno
Townsend, 1916
| 1 | Species |
| Genus | Bactromyia
Brauer & von Bergenstamm, 1891
| 18 | Species |
| Genus | Bactromyiella
Mesnil, 1952
| 2 | Species |
| Genus | Buquetia
Robineau-Desvoidy, 1847
| 4 | Species |
| Genus | Cadurciella
Villeneuve, 1927
| 4 | Species |
| Genus | Carcelia
Robineau-Desvoidy, 1830
| 281 | Species |
| Genus | Catagonia
Brauer & von Bergenstamm, 1891 ⇒ Apogonia (Apogonia)
| 4 | Species |
| Genus | Catagoniopsis
Townsend, 1926 ⇒ Patelloa
| 4 | Species |
| Genus | Cestonionerva
Villeneuve, 1929
| 4 | Species |
| Genus | Chlorogastropsis
Townsend, 1926
| 1 | Species |
| Genus | Diglossocera
van der Wulp, 1895
| 1 | Species |
| Genus | Drino
Robineau-Desvoidy, 1863
| 141 | Species |
| Genus | Epicampocera
Macquart, 1849
| 2 | Species |
| Genus | Erycesta
Macquart, 1849
| 2 | Species |
| Genus | Erycia
Robineau-Desvoidy, 1830
| 47 | Species |
| Genus | Eufrontina
Brooks, 1945 ⇒ Frontiniella
| 2 | Species |
| Genus | Euhygia
Mesnil, 1968
| 2 | Species |
| Genus | Eunemorilla
Townsend, 1919
| 11 | Species |
| Genus | Gymnophryxe
Villeneuve, 1924
| 9 | Species |
| Genus | Hapalioloemus
Baranov, 1934
| 2 | Species |
| Genus | Heliodorus
Reinhard, 1964
| 2 | Species |
| Genus | Hubneria
Robineau-Desvoidy, 1848 ⇒ Huebneria
| 27 | Species |
| Genus | Huebneria
Robineau-Desvoidy, 1847
| 5 | Species |
| Genus | Isosturmia
Townsend, 1927
| 13 | Species |
| Genus | Lespesia
Robineau-Desvoidy, 1863
| 76 | Species |
| Genus | Lydella
Robineau-Desvoidy, 1830
| 94 | Species |
| Genus | Madremyia
Townsend, 1916
| 4 | Species |
| Genus | Metagonistylum
Robineau-Desvoidy, 1830 ⇒ Diatraeophaga
| 3 | Species |
| Genus | Metaphryno
Crosskey, 1967
| 1 | Species |
| Genus | Myothyriopsis
Townsend, 1919
| 2 | Species |
| Genus | Neomedina
Malloch, 1935
| 1 | Species |
| Genus | Nilea
Robineau-Desvoidy, 1863
| 48 | Species |
| Genus | Obolocera
Townsend, 1919 ⇒ Phryxe
| 1 | Species |
| Genus | Paradrino
Mesnil, 1949
| 11 | Species |
| Genus | Parapales
Mesnil, 1950
| 8 | Species |
| Genus | Periarchiclops
Villeneuve, 1924
| 1 | Species |
| Genus | Phebellia
Robineau-Desvoidy, 1846
| 44 | Species |
| Genus | Phonomyia
Robineau-Desvoidy, 1893
| 5 | Species |
| Genus | Phorocerostoma
Malloch, 1930
| 1 | Species |
| Genus | Phryxe
Robineau-Desvoidy, 1830
| 292 | Species |
| Genus | Pilatea
Townsend, 1916 ⇒ Allophorocera
| 3 | Species |
| Genus | Prooppia
Townsend, 1926 ⇒ Aplomya
| 6 | Species |
| Genus | Prophryno
Townsend, 1927 ⇒ Lespesia
| 2 | Species |
| Genus | Pseudoperichaeta
Brauer & von Bergenstamm, 1889 ⇒ Nilea
| 20 | Species |
| Genus | Ptesiomyia
Brauer & von Bergenstamm, 1893
| 3 | Species |
| Genus | Rhinaplomyia
Mesnil, 1955
| 3 | Species |
| Genus | Rhinomyodes
Townsend, 1933
| 1 | Species |
| Genus | Senometopia
Macquart, 1834 ⇒ Carcelia (Carcelia)
| 108 | Species |
| Genus | Setalunula
Chao & Yang, 1990
| 2 | Species |
| Genus | Siphosturmia
Coquillett, 1897
| 12 | Species |
| Genus | Sisyropa
Brauer & von Bergenstamm, 1889
| 31 | Species |
| Genus | Sturmiopsis
Townsend, 1916
| 6 | Species |
| Genus | Teretrophora
Macquart, 1851
| 1 | Species |
| Genus | Thecocarcelia
Townsend, 1933
| 30 | Species |
| Genus | Thelyconychia
Brauer & von Bergenstamm, 1889
| 10 | Species |
| Genus | Thelymyia
Brauer & von Bergenstamm, 1891
| 5 | Species |
| Genus | Tlephusa
Robineau-Desvoidy, 1863
| 5 | Species |
| Genus | Townsendiellomyia
Baranov, 1932
| 1 | Species |
| Genus | Tryphera
Meigen, 1838
| 5 | Species |
| Genus | Tsugaea
Hall, 1939
| 1 | Species |
| Genus | Weingaertneriella
Baranov, 1932
| 1 | Species |
| Genus | Xylotachina
Brauer & von Bergenstamm, 1891
| 3 | Species |
| Genus | Zizyphomyia
Townsend, 1916
| 6 | Species |
