| Astacus pallipes (Lereboullet, 1858) | ⇒ Austropotamobius pallipes Lereboullet, 1858 |
| Barbicambarus simmonsi Taylor & Sch..., 2010 | Tennessee Bottlebrush Crayfish |
| Cambarellus (Dirigicambarus) shufeldtii Faxon, 1884 | Cajun dwarf crayfish |
| Cambarellus (Pandicambarus) diminutus Hobbs, 1945 | Least caryfish |
| Cambarellus (Pandicambarus) lesliei Fitzpatrick ..., 1976 | Angular dwarf crawfish |
| Cambarellus (Pandicambarus) schmitti Hobbs, 1942 | Fontal Dwarf Crawfish |
| Cambarellus rotatus Schuster & K..., 2017 | Twisted Dwarf Crayfish |
| Cambarus (Aviticambarus) hamulatus Cope, 1881 | Prickly cave crayfish |
| Cambarus (Aviticambarus) jonesi Hobbs & Barr, 1960 | Alabama cave crayfish |
| Cambarus (Aviticambarus) laconensis Buhay & Cran..., 2009 | Lacon Exit cave crayfish |
| Cambarus (Aviticambarus) pecki Hobbs, 1967 | Phantom cave crayfish |
| Cambarus (Aviticambarus) speleocoopi Buhay & Cran..., 2009 | Sweet Home Alabama cave crayfish |
| Cambarus (Aviticambarus) veitchorum J. E. Cooper..., 1997 | White Spring cave crayfish |
| Cambarus (Cambarus) bartonii Fabricius, 1798 | Appalachian brook crayfish |
| Cambarus (Cambarus) howardi Hobbs & Hall, 1969 | Chattahoochee crayfish |
| Cambarus (Depressicambarus) clairitae Schuster & T..., 2016 | Zebra Crayfish |
| Cambarus (Depressicambarus) englishi Hobbs & Hall, 1972 | Tallapoosa Crayfish |
| Cambarus (Depressicambarus) graysoni Faxon, 1914 | Two-spot crayfish |
| Cambarus (Depressicambarus) halli Hobbs, 1968 | Slackwater Crayfish |
| Cambarus (Depressicambarus) latimanus Le Conte, 1856 | Variable Crayfish |
| Cambarus (Depressicambarus) obstipus Hall, 1959 | Sloped Crayfish |
| Cambarus (Depressicambarus) pyronotus R. W. Bouchard, 1978 | Fireback crayfish |
| Cambarus (Depressicambarus) reduncus Hobbs, 1956 | Sickle Crayfish |
| Cambarus (Depressicambarus) sphenoides Hobbs, 1968 | Triangleclaw Crayfish |
| Cambarus (Depressicambarus) striatus Hay, 1902 | Ambiguous Crayfish |
| Cambarus (Depressicambarus) strigosus Hobbs, 1981 | Lean Crayfish |
| Cambarus (Erebicambarus) rusticiformis Rhoades, 1944 | Depression crayfish |
| Cambarus (Erebicambarus) tenebrosus Hay, 1902 | Cavespring crayfish |
| Cambarus (Exilicambarus) cracens R. W. Boucha..., 1976 | Slenderclaw Crayfish |
| Cambarus (Hiaticambarus) andersoni Jones & Ever..., 2015 | Florence Crayfish |
| Cambarus (Hiaticambarus) chasmodactylus James, 1966 | New River crayfish |
| Cambarus (Hiaticambarus) diupalma Jones & Ever..., 2015 | Mountain Fork Crayfish |
| Cambarus (Hiaticambarus) girardianus Faxon, 1884 | Tanback Crayfish |
| Cambarus (Hiaticambarus) longirostris Faxon, 1885 | Longnose Crayfish |
| Cambarus (Hiaticambarus) longulus Girard, 1852 | Atlantic Slope Crayfish |
| Cambarus (Hiaticambarus) manningi Hobbs, 1981 | Greensaddle Crayfish |
| Cambarus (Jugicambarus) asperimanus Faxon, 1914 | Mitten Crayfish |
| Cambarus (Jugicambarus) distans Rhoades, 1944 | Boxclaw crawfish |
| Cambarus (Jugicambarus) dubius Faxon, 1884 | Upland burrowing crayfish |
| Cambarus (Jugicambarus) parvoculus Hobbs & Shoup, 1947 | Mountain midget crayfish |
| Cambarus (Jugicambarus) unestami Hobbs & Hall, 1969 | Blackbarred Crayfish |
| Cambarus (Lacunicambarus) diogenes Girard, 1852 | Chimney crayfish |
| Cambarus (Lacunicambarus) ludovicianus Faxon, 1884 | Painted devil crayfish |
| Cambarus (Lacunicambarus) miltus Fitzpatrick, 1978 | Rusty grave digger |
| Cambarus (Puncticambarus) acuminatus Faxon, 1884 | Acuminate Crayfish |
| Cambarus (Puncticambarus) aldermanorum Cooper & Price, 2010 | Carolina Needlenose Crayfish |
| Cambarus (Puncticambarus) buntingi R. W. Bouchard, 1973 | Bunting crayfish |
| Cambarus (Puncticambarus) coosae Hobbs, 1981 | Coosa Crayfish |
| Cambarus (Puncticambarus) extraneus Hagen, 1870 | Chickamauga crayfish |
| Cambarus (Puncticambarus) hobbsorum J. E. Cooper, 2001 | Rocky River crayfish |
| Cambarus (Puncticambarus) johni Cooper, 2006 | Carolina Foothills Crayfish |
| Cambarus (Puncticambarus) robustus Girard, 1852 | Big water crayfish |
| Cambarus (Puncticambarus) scotti Hobbs, 1981 | Chatooga crayfish |
| Cambarus (Tubericambarus) acanthura Hobbs, 1981 | Thornytail Crayfish |
| Cambarus (Tubericambarus) thomai Jezerinac, 1993 | Little brown mudbug |
| Cambarus cahni Rhoades, 1944 | |
| Cambarus jordani Faxon, 1884 | |
| Creaserinus burrisi Fitzpatrick, 1987 | Burrowing bog crayfish |
| Creaserinus danielae Hobbs, 1975 | Speckled burrowing crayfish |
| Fallicambarus (Creaserinus) burrisi Fitzpatrick, 1987 | Burrowing bog crayfish |
| Fallicambarus (Creaserinus) byersi Hobbs, 1941 | Lavender burrowing crayfish |
| Fallicambarus (Creaserinus) danielae Hobbs, 1975 | Speckled burrowing crayfish |
| Fallicambarus (Creaserinus) fodiens Cottle, 1863 | Digger crayfish |
| Fallicambarus (Creaserinus) hedgpethi Hobbs, 1948 | |
| Fallicambarus (Creaserinus) oryktes Penn & Marlow, 1959 | Flatwoods Digger |
| Faxonella clypeata Hay, 1899 | Ditch fencing crayfish |
| Faxonius juvenilis Hagen, 1870 | Kentucky River Crayfish |
| Faxonius taylori Schuster, 2008 | Crescent Crayfish |
| Faxonius yanahlindus Taylor, Rhod..., 2016 | Spinywrist Crayfish |
| Hobbseus attenuatus Black, 1969 | Pearl riverlet crayfish |
| Hobbseus cristatus Hobbs, 1955 | Crested Riverlet Crayfish |
| Hobbseus orconectoides Fitzpatrick ..., 1968 | Oktibbeha riverlet crayfish |
| Hobbseus petilus Fitzpatrick, 1977 | Tombigbee riverlet crayfish |
| Hobbseus prominens Hobbs, 1966 | Prominence Riverlet Crayfish |
| Hobbseus valleculus Fitzpatrick, 1967 | Choctaw riverlet crayfish |
| Hobbseus valobushensis Fitzpatrick ..., 1989 | |
| Hoploparia johnsoni Rathbun, 1935 | |
| Hoploparia tennesseensis ♰ Rathbun & Wade, 1926 | |
| Lacunicambarus erythrodactylus Simon & Morris, 2014 | Warpaint Mudbug |
| Lacunicambarus polychromatus Thoma, Jezer..., 2005 | Paintedhand Mudbug |
| Nephropsis aculeata Smith, 1881 | Florida lobsterette |
| Orconectes (Buannulifictus) meeki Williams, 1952 | Meek crayfish |
| Orconectes (Crockerinus) erichsonianus Faxon, 1898 | Reticulate crayfish |
| Orconectes (Crockerinus) rafinesquei Rhoades, 1944 | Rafinesque crayfish |
| Orconectes (Faxonius) limosus Rafinesque, 1817 | Delcore Crayfish |
| Orconectes (Gremicambarus) alabamensis Faxon, 1884 | |
| Orconectes (Gremicambarus) compressus Faxon, 1884 | Slender crayfish |
| Orconectes (Gremicambarus) jonesi Fitzpatrick, 1992 | Sucarnoochee crayfish |
| Orconectes (Gremicambarus) virilis Hagen, 1870 | Common Crawfish |
| Orconectes (Hespericambarus) hartfieldi Fitzpatrick ..., 1992 | Yazoo crayfish |
| Orconectes (Hespericambarus) hathawayi Penn, 1952 | Teche Painted Crawfish |
| Orconectes (Hespericambarus) perfectus Walls, 1972 | Complete crayfish |
| Orconectes (Orconectes) australis Rhoades, 1941 | Appalachian Cave Crayfish |
| Orconectes (Orconectes) pellucidus Tellkampf, 1844 | Mammoth Cave crayfish |
| Orconectes (Orconectes) sheltae J. R. Cooper..., 1997 | Kiamichi crayfish |
| Orconectes (Procericambarus) carolinensis J. E. Cooper..., 1995 | North Carolina crayfish |
| Orconectes (Procericambarus) durelli R. W. Boucha..., 1995 | Saddle crayfish |
| Orconectes (Procericambarus) forceps Faxon, 1884 | Surgeon crayfish |
| Orconectes (Procericambarus) mirus Ortmann, 1931 | Wonderful crayfish |
| Orconectes (Procericambarus) placidus Hagen, 1870 | Bigclaw crayfish |
| Orconectes (Procericambarus) rusticus Girard, 1852 | Rusty crayfish |
| Orconectes (Procericambarus) spinosus Bundy, 1877 | Coona River spiny crayfish |
| Orconectes (Tragulicambarus) lancifer Hagen, 1870 | Shrimp crayfish |
| Orconectes (Trisellescens) alabamensis Faxon, 1884 | Alabama crayfish |
| Orconectes (Trisellescens) chickasawae Cooper & Hobbs, 1980 | Chickasaw crayfish |
| Orconectes (Trisellescens) cooperi Cooper & Hobbs, 1980 | Flint River crayfish |
| Orconectes (Trisellescens) etnieri Bouchard & B..., 1976 | Ets crayfish |
| Orconectes (Trisellescens) holti Cooper & Hobbs, 1980 | Bimaculate crayfish |
| Orconectes (Trisellescens) immunis Hagen, 1870 | Calico crayfish |
| Orconectes (Trisellescens) rhoadesi Hobbs, 1949 | Fishhook crayfish |
| Orconectes (Trisellescens) validus Faxon, 1914 | Powerful crayfish |
| Procambarus (Girardiella) curdi Reimer, 1975 | Red River Burrowing Crayfish |
| Procambarus (Girardiella) hagenianus Faxon, 1884 | Egyptian Crayfish |
| Procambarus (Girardiella) holifieldi Schuster, Ta..., 2015 | Celestial Crayfish |
| Procambarus (Leconticambarus) capillatus Hobbs, 1971 | Capillaceous Crayfish |
| Procambarus (Leconticambarus) escambiensis Hobbs, 1942 | Escambia crayfish |
| Procambarus (Leconticambarus) hubbelli Hobbs, 1940 | Jackknife Crayfish |
| Procambarus (Leconticambarus) shermani Hobbs, 1942 | Gulf Crayfish |
| Procambarus (Ortmannicus) acutissimus Girard, 1852 | Sharpnose Crayfish |
| Procambarus (Ortmannicus) acutus Girard, 1852 | White river crawfish |
| Procambarus (Ortmannicus) bivittatus Hobbs, 1942 | Ribbon crayfish |
| Procambarus (Ortmannicus) blandingii Harlan, 1830 | Santee Crayfish |
| Procambarus (Ortmannicus) chacei Hobbs, 1958 | Cedar Creek Crayfish |
| Procambarus (Ortmannicus) evermanni Faxon, 1890 | Panhandle Crayfish |
| Procambarus (Ortmannicus) hayi Faxon, 1884 | Straightedge Crayfish |
| Procambarus (Ortmannicus) hybus Hobbs & Walton, 1957 | Smoothnose Crayfish |
| Procambarus (Ortmannicus) lecontei Hagen, 1870 | Mobile crayfish |
| Procambarus (Ortmannicus) lepidodactylus Hobbs, 1947 | Pee Dee lotic crayfish |
| Procambarus (Ortmannicus) lewisi Hobbs & Walton, 1959 | Spur Crayfish |
| Procambarus (Ortmannicus) lophotus Hobbs & Walton, 1960 | Mane Crayfish |
| Procambarus (Ortmannicus) marthae Hobbs, 1975 | Crisscross Crayfish |
| Procambarus (Ortmannicus) seminolae Hobbs, 1942 | Seminole crayfish |
| Procambarus (Ortmannicus) verrucosus Hobbs, 1952 | Grainy Crayfish |
| Procambarus (Ortmannicus) viaeviridis Faxon, 1914 | Vernal crayfish |
| Procambarus (Ortmannicus) zonangulus Hobbs & Hobbs, 1990 | Southern White River Crawfish |
| Procambarus (Pennides) clemmeri Hobbs, 1975 | Cockscomb Crayfish |
| Procambarus (Pennides) elegans Hobbs, 1969 | Elegant Creek Crayfish |
| Procambarus (Pennides) gibbus Hobbs, 1969 | Muckalee Crayfish |
| Procambarus (Pennides) lagniappe Black, 1968 | Lagniappe crayfish |
| Procambarus (Pennides) lylei Fitzpatrick ..., 1971 | Shutispear crayfish |
| Procambarus (Pennides) penni Hobbs, 1951 | Pearl blackwater crayfish |
| Procambarus (Pennides) spiculifer LeConte, 1856 | White Tubercled Crayfish |
| Procambarus (Pennides) suttkusi Hobbs, 1953 | Choctawhatchee Crayfish |
| Procambarus (Pennides) versutus Hagen, 1870 | Sly Crayfish |
| Procambarus (Pennides) vioscai Penn, 1946 | Burnham's blackberry |
| Procambarus (Remoticambarus) pecki (Hobbs, 1967) | ⇒ Cambarus pecki Hobbs, 1967 |
| Procambarus (Scapulicambarus) clarkii Girard, 1852 | American crayfish |
| Procambarus (Scapulicambarus) okaloosae Hobbs, 1942 | Okaloosa Crayfish |
| Procambarus (Scapulicambarus) paeninsulanus Faxon, 1914 | Peninsula Crayfish |
