| Astacus astacus Linnaeus, 1758 | Broad-clawed Crayfish |
| Astacus fluviatilis (Linnaeus, 1758) | ⇒ Astacus leptodactylus Eschscholtz, 1823 |
| Astacus pallipes (Lereboullet, 1858) | ⇒ Austropotamobius pallipes Lereboullet, 1858 |
| Austropotamobius torrentium Schrank, 1803 | Stone crayfish |
| Cambarellus (Pandicambarus) ninae Hobbs, 1950 | Aransas Dwarf Crawfish |
| Cambarellus (Pandicambarus) puer Hobbs, 1941 | Swamp dwarf crayfish |
| Cambarus (Cambarus) angularis Hobbs & R. W..., 1994 | Angled Crayfish |
| Cambarus (Cambarus) bartonii Fabricius, 1798 | Appalachian brook crayfish |
| Cambarus (Depressicambarus) halli Hobbs, 1968 | Slackwater Crayfish |
| Cambarus (Depressicambarus) latimanus Le Conte, 1856 | Variable Crayfish |
| Cambarus (Depressicambarus) reduncus Hobbs, 1956 | Sickle Crayfish |
| Cambarus (Depressicambarus) striatus Hay, 1902 | Ambiguous Crayfish |
| Cambarus (Erebicambarus) hubrichti Hobbs, 1952 | Salem cave crayfish |
| Cambarus (Erebicambarus) tenebrosus Hay, 1902 | Cavespring crayfish |
| Cambarus (Hiaticambarus) chasmodactylus James, 1966 | New River crayfish |
| Cambarus (Hiaticambarus) fasciatus Hobbs, 1981 | Etowah crayfish |
| Cambarus (Hiaticambarus) longulus Girard, 1852 | Atlantic Slope Crayfish |
| Cambarus (Jugicambarus) asperimanus Faxon, 1914 | Mitten Crayfish |
| Cambarus (Jugicambarus) carolinus Erichson, 1846 | Red Burrowing Crayfish |
| Cambarus (Jugicambarus) conasaugaensis Hobbs & Hobb..., 1962 | Mountain Crayfish |
| Cambarus (Jugicambarus) distans Rhoades, 1944 | Boxclaw crawfish |
| Cambarus (Jugicambarus) dubius Faxon, 1884 | Upland burrowing crayfish |
| Cambarus (Jugicambarus) magerae Thoma & Fetzner, 2015 | Big Stone Crayfish |
| Cambarus (Jugicambarus) parvoculus Hobbs & Shoup, 1947 | Mountain midget crayfish |
| Cambarus (Lacunicambarus) diogenes Girard, 1852 | Chimney crayfish |
| Cambarus (Puncticambarus) acuminatus Faxon, 1884 | Acuminate Crayfish |
| Cambarus (Puncticambarus) coosae Hobbs, 1981 | Coosa Crayfish |
| Cambarus (Puncticambarus) cumberlandensis Hobbs & R. W..., 1973 | Cumberland crayfish |
| Cambarus (Puncticambarus) hobbsorum J. E. Cooper, 2001 | Rocky River crayfish |
| Cambarus (Puncticambarus) johni Cooper, 2006 | Carolina Foothills Crayfish |
| Cambarus (Puncticambarus) reburrus Prins, 1968 | French Broad crayfish |
| Cambarus (Puncticambarus) robustus Girard, 1852 | Big water crayfish |
| Cambarus (Puncticambarus) scotti Hobbs, 1981 | Chatooga crayfish |
| Cambarus (Puncticambarus) theepiensis Loughman, Fo..., 2013 | Coalfields Crayfish |
| Cambarus (Tubericambarus) acanthura Hobbs, 1981 | Thornytail Crayfish |
| Cambarus (Tubericambarus) thomai Jezerinac, 1993 | Little brown mudbug |
| Cambarus hazardi Loughman, He..., 2017 | Brawny Crayfish |
| Cambarus jordani Faxon, 1884 | |
| Creaserinus fodiens Cottle, 1863 | Digger crayfish |
| Distocambarus (Distocambarus) crockeri Hobbs and Ca..., 1983 | Piedmont Prairie Burrowing Crayfish |
| Fallicambarus (Creaserinus) danielae Hobbs, 1975 | Speckled burrowing crayfish |
| Fallicambarus (Creaserinus) fodiens Cottle, 1863 | Digger crayfish |
| Fallicambarus (Creaserinus) hedgpethi Hobbs, 1948 | |
| Fallicambarus (Creaserinus) uhleri Faxon, 1884 | |
| Faxonella blairi Hayes & Reimer, 1977 | Blair's fencing crayfish |
| Faxonella clypeata Hay, 1899 | Ditch fencing crayfish |
| Faxonius immunis Hagen, 1870 | Calico Crayfish |
| Faxonius juvenilis Hagen, 1870 | Kentucky River Crayfish |
| Faxonius limosus Rafinesque, 1817 | American Crayfish |
| Faxonius neglectus Faxon, 1885 | Gap Ringed Crayfish |
| Faxonius neglectus chaenodactylus Williams, 1952 | Gap Ringed Crayfish |
| Faxonius rusticus Girard, 1852 | Rusty crayfish |
| Faxonius virilis Hagen, 1870 | Virile Crayfish |
| Hobbseus prominens Hobbs, 1966 | Prominence Riverlet Crayfish |
| Lacunicambarus erythrodactylus Simon & Morris, 2014 | Warpaint Mudbug |
| Orconectes (Buannulifictus) meeki Williams, 1952 | Meek crayfish |
| Orconectes (Crockerinus) erichsonianus Faxon, 1898 | Reticulate crayfish |
| Orconectes (Crockerinus) marchandi Hobbs, 1948 | Mammoth Spring crayfish |
| Orconectes (Crockerinus) propinquus Girard, 1852 | Northern clearwater crayfish |
| Orconectes (Crockerinus) rafinesquei Rhoades, 1944 | Rafinesque crayfish |
| Orconectes (Crockerinus) sanbornii Faxon, 1884 | Sanborn crayfish |
| Orconectes (Faxonius) limosus Rafinesque, 1817 | Delcore Crayfish |
| Orconectes (Gremicambarus) compressus Faxon, 1884 | Slender crayfish |
| Orconectes (Gremicambarus) jonesi Fitzpatrick, 1992 | Sucarnoochee crayfish |
| Orconectes (Gremicambarus) virilis Hagen, 1870 | Common Crawfish |
| Orconectes (Hespericambarus) difficilis Faxon, 1898 | Painted crayfish |
| Orconectes (Procericambarus) carolinensis J. E. Cooper..., 1995 | North Carolina crayfish |
| Orconectes (Procericambarus) cristavarius Taylor, 2000 | Spiny stream crayfish |
| Orconectes (Procericambarus) durelli R. W. Boucha..., 1995 | Saddle crayfish |
| Orconectes (Procericambarus) forceps Faxon, 1884 | Surgeon crayfish |
| Orconectes (Procericambarus) luteus Creaser, 1933 | Golden crayfish |
| Orconectes (Procericambarus) mirus Ortmann, 1931 | Wonderful crayfish |
| Orconectes (Procericambarus) neglectus Williams, 1952 | Gap Ringed Crayfish |
| Orconectes (Procericambarus) ozarkae A. B. Williams, 1952 | Ozark crayfish |
| Orconectes (Procericambarus) placidus Hagen, 1870 | Bigclaw crayfish |
| Orconectes (Procericambarus) punctimanus Creaser, 1933 | Spothand crayfish |
| Orconectes (Procericambarus) putnami Faxon, 1884 | Phallic crayfish |
| Orconectes (Procericambarus) rusticus Girard, 1852 | Rusty crayfish |
| Orconectes (Trisellescens) cooperi Cooper & Hobbs, 1980 | Flint River crayfish |
| Orconectes (Trisellescens) immunis Hagen, 1870 | Calico crayfish |
| Orconectes (Trisellescens) mississippiensis Faxon, 1884 | Mississippi crayfish |
| Pacifastacus (Pacifastacus) leniusculus Dana, 1852 | American Signal Crayfish |
| Pontastacus leptodactylus Eschscholtz, 1823 | Danube Crayfish |
| Procambarus (Austrocambarus) cubensis Erichson, 1846 | |
| Procambarus (Capillicambarus) brazoriensis Albaugh, 1975 | Brazoria crayfish |
| Procambarus (Girardiella) ceruleus Fitzpatrick ..., 1998 | Blueclaw Chimney Crawfish |
| Procambarus (Girardiella) gracilis Bundy, 1876 | Prairie crayfish |
| Procambarus (Girardiella) tulanei Penn, 1953 | Giant Bearded Crayfish |
| Procambarus (Hagenides) talpoides Hobbs, 1981 | Mole Crayfish |
| Procambarus (Leconticambarus) barbatus Faxon, 1890 | Wandering Crayfish |
| Procambarus (Ortmannicus) acutus Girard, 1852 | White river crawfish |
| Procambarus (Ortmannicus) ancylus Hobbs, 1958 | Coastal Plain Crayfish |
| Procambarus (Ortmannicus) blandingii Harlan, 1830 | Santee Crayfish |
| Procambarus (Ortmannicus) braswelli J. E. Cooper, 1998 | Waccamaw crayfish |
| Procambarus (Ortmannicus) fallax Hagen, 1870 | Deceitful Crayfish |
| Procambarus fallax virginalis Martin & al., 2010 | Marbled Crayfish |
| Procambarus (Ortmannicus) geminus Hobbs, 1975 | Twin Crawfish |
| Procambarus (Ortmannicus) hayi Faxon, 1884 | Straightedge Crayfish |
| Procambarus (Ortmannicus) hirsutus Hobbs, 1958 | Shaggy Crayfish |
| Procambarus (Ortmannicus) leonensis Hobbs, 1942 | Blacknose Crayfish |
| Procambarus (Ortmannicus) lewisi Hobbs & Walton, 1959 | Spur Crayfish |
| Procambarus (Ortmannicus) lunzi Hobbs, 1940 | Hummock Crayfish |
| Procambarus (Ortmannicus) pearsei Creaser, 1934 | Carolina Sandhills Crayfish |
| Procambarus (Ortmannicus) pubescens Faxon, 1884 | Brushnose Crayfish |
| Procambarus (Ortmannicus) pycnogonopodus Hobbs, 1942 | Stud Crayfish |
| Procambarus (Ortmannicus) verrucosus Hobbs, 1952 | Grainy Crayfish |
| Procambarus (Pennides) clemmeri Hobbs, 1975 | Cockscomb Crayfish |
| Procambarus (Pennides) echinatus Hobbs, 1956 | Edisto crayfish |
| Procambarus (Pennides) petersi Hobbs, 1981 | Ogeechee Crayfish |
| Procambarus (Pennides) roberti Villalobos &..., 1974 | |
| Procambarus (Pennides) spiculifer LeConte, 1856 | White Tubercled Crayfish |
| Procambarus (Pennides) suttkusi Hobbs, 1953 | Choctawhatchee Crayfish |
| Procambarus (Pennides) versutus Hagen, 1870 | Sly Crayfish |
| Procambarus (Pennides) vioscai Penn, 1946 | Burnham's blackberry |
| Procambarus (Scapulicambarus) clarkii Girard, 1852 | American crayfish |
| Procambarus (Scapulicambarus) howellae Hobbs, 1952 | Ornate Crayfish |
| Procambarus (Scapulicambarus) troglodytes LeConte, 1856 | Eastern Red Swamp Crawfish |
| Procambarus virginalis Lyko, 2017 | Marbled crayfish |
