| Cambarus (Bartonius) bartoni Rhoades, 1944 | |
| Cambarus (Cambarus) angularis Hobbs & R. W..., 1994 | Angled Crayfish |
| Cambarus (Cambarus) bartonii Fabricius, 1798 | Appalachian brook crayfish |
| Cambarus (Cambarus) carinirostris Hay, 1914 | Rock crawfish |
| Cambarus (Cambarus) hatfieldi Loughman, Fa..., 2013 | Tug Valley Crayfish |
| Cambarus (Cambarus) howardi Hobbs & Hall, 1969 | Chattahoochee crayfish |
| Cambarus (Cambarus) sciotensis Rhoades, 1944 | Teays River crayfish |
| Cambarus (Depressicambarus) graysoni Faxon, 1914 | Two-spot crayfish |
| Cambarus (Depressicambarus) latimanus Le Conte, 1856 | Variable Crayfish |
| Cambarus (Depressicambarus) reduncus Hobbs, 1956 | Sickle Crayfish |
| Cambarus (Depressicambarus) striatus Hay, 1902 | Ambiguous Crayfish |
| Cambarus (Erebicambarus) tenebrosus Hay, 1902 | Cavespring crayfish |
| Cambarus (Hiaticambarus) chasmodactylus James, 1966 | New River crayfish |
| Cambarus (Hiaticambarus) girardianus Faxon, 1884 | Tanback Crayfish |
| Cambarus (Hiaticambarus) longirostris Faxon, 1885 | Longnose Crayfish |
| Cambarus (Hiaticambarus) longulus Girard, 1852 | Atlantic Slope Crayfish |
| Cambarus (Jugicambarus) asperimanus Faxon, 1914 | Mitten Crayfish |
| Cambarus (Jugicambarus) carolinus Erichson, 1846 | Red Burrowing Crayfish |
| Cambarus (Jugicambarus) distans Rhoades, 1944 | Boxclaw crawfish |
| Cambarus (Jugicambarus) dubius Faxon, 1884 | Upland burrowing crayfish |
| Cambarus (Jugicambarus) jezerinaci Thoma, 2000 | Spiny Scale Crayfish |
| Cambarus (Jugicambarus) magerae Thoma & Fetzner, 2015 | Big Stone Crayfish |
| Cambarus (Jugicambarus) monongalensis Ortmann, 1905 | Blue Crawfish |
| Cambarus (Jugicambarus) parvoculus Hobbs & Shoup, 1947 | Mountain midget crayfish |
| Cambarus (Lacunicambarus) diogenes Girard, 1852 | Chimney crayfish |
| Cambarus (Puncticambarus) acuminatus Faxon, 1884 | Acuminate Crayfish |
| Cambarus (Puncticambarus) buntingi R. W. Bouchard, 1973 | Bunting crayfish |
| Cambarus (Puncticambarus) callainus Thoma, Lough..., 2014 | Big Sandy Crayfish |
| Cambarus (Puncticambarus) hiwasseensis Hobbs, 1981 | Hiwassee crayfish |
| Cambarus (Puncticambarus) parrishi Hobbs, 1981 | Hiwassee headwater crayfish |
| Cambarus (Puncticambarus) robustus Girard, 1852 | Big water crayfish |
| Cambarus (Puncticambarus) theepiensis Loughman, Fo..., 2013 | Coalfields Crayfish |
| Cambarus (Puncticambarus) veteranus Faxon, 1914 | Big Sandy crayfish |
| Cambarus (Tubericambarus) acanthura Hobbs, 1981 | Thornytail Crayfish |
| Cambarus appalachiensis Loughman, We..., 2017 | Conhaway Crayfish |
| Cambarus guenteri Loughman, He..., 2017 | Redbird Crayfish |
| Fallicambarus (Creaserinus) fodiens Cottle, 1863 | Digger crayfish |
| Fallicambarus (Creaserinus) uhleri Faxon, 1884 | |
| Orconectes (Crockerinus) erichsonianus Faxon, 1898 | Reticulate crayfish |
| Orconectes (Crockerinus) obscurus Hagen, 1870 | Allegheny crayfish |
| Orconectes (Crockerinus) propinquus Girard, 1852 | Northern clearwater crayfish |
| Orconectes (Crockerinus) rafinesquei Rhoades, 1944 | Rafinesque crayfish |
| Orconectes (Crockerinus) virginiensis Hobbs, 1951 | Chowanoke crayfish |
| Orconectes (Faxonius) limosus Rafinesque, 1817 | Delcore Crayfish |
| Orconectes (Gremicambarus) compressus Faxon, 1884 | Slender crayfish |
| Orconectes (Gremicambarus) virilis Hagen, 1870 | Common Crawfish |
| Orconectes (Hespericambarus) perfectus Walls, 1972 | Complete crayfish |
| Orconectes (Procericambarus) carolinensis J. E. Cooper..., 1995 | North Carolina crayfish |
| Orconectes (Procericambarus) cristavarius Taylor, 2000 | Spiny stream crayfish |
| Orconectes (Procericambarus) forceps Faxon, 1884 | Surgeon crayfish |
| Orconectes (Procericambarus) longidigitus Faxon, 1898 | Longpincered crayfish |
| Orconectes (Procericambarus) mirus Ortmann, 1931 | Wonderful crayfish |
| Orconectes (Procericambarus) ozarkae A. B. Williams, 1952 | Ozark crayfish |
| Orconectes (Procericambarus) placidus Hagen, 1870 | Bigclaw crayfish |
| Orconectes (Procericambarus) putnami Faxon, 1884 | Phallic crayfish |
| Orconectes (Procericambarus) rusticus Girard, 1852 | Rusty crayfish |
| Orconectes (Procericambarus) spinosus Bundy, 1877 | Coona River spiny crayfish |
| Procambarus (Hagenides) advena LeConte, 1856 | Vidalia Crayfish |
| Procambarus (Ortmannicus) acutissimus Girard, 1852 | Sharpnose Crayfish |
| Procambarus (Ortmannicus) acutus Girard, 1852 | White river crawfish |
| Procambarus (Ortmannicus) angustatus LeConte, 1856 | Sandhills crayfish |
| Procambarus (Ortmannicus) blandingii Harlan, 1830 | Santee Crayfish |
| Procambarus (Ortmannicus) chacei Hobbs, 1958 | Cedar Creek Crayfish |
| Procambarus (Ortmannicus) fallax Hagen, 1870 | Deceitful Crayfish |
| Procambarus (Ortmannicus) hayi Faxon, 1884 | Straightedge Crayfish |
| Procambarus (Ortmannicus) lophotus Hobbs & Walton, 1960 | Mane Crayfish |
| Procambarus (Ortmannicus) seminolae Hobbs, 1942 | Seminole crayfish |
| Procambarus (Ortmannicus) verrucosus Hobbs, 1952 | Grainy Crayfish |
| Procambarus (Ortmannicus) zonangulus Hobbs & Hobbs, 1990 | Southern White River Crawfish |
| Procambarus (Pennides) ouachitae Penn, 1956 | Ouachita River Crayfish |
| Procambarus (Pennides) versutus Hagen, 1870 | Sly Crayfish |
| Procambarus (Scapulicambarus) clarkii Girard, 1852 | American crayfish |
| Procambarus (Scapulicambarus) howellae Hobbs, 1952 | Ornate Crayfish |
| Procambarus (Scapulicambarus) troglodytes LeConte, 1856 | Eastern Red Swamp Crawfish |
