| Chymomyza aldrichii Sturtevant, 1916 | Mexican buckeye |
| Chymomyza amoena Loew, 1862 | |
| Chymomyza caudatula Oldenberg, 1914 | Side-flower miterwort |
| Chymomyza coxata Wheeler, 1952 | Ivyleaf groundcherry |
| Chymomyza olympia Wheeler, 1960 | |
| Chymomyza procnemis Williston, 1896 | Fly |
| Chymomyza procnemoides Wheeler, 1952 | Ivyleaf groundcherry |
| Chymomyza wirthi Wheeler, 1954 | Clammy groundcherry |
| Dettopsomyia nigrovittata Malloch, 1924 | Pomace fly |
| Drosophila (Dorsidorpha) busckii Cocquillett, 1901 | |
| Drosophila (Drosophila) aldrichi Patterson & ..., 1940 | Prickly rose |
| Drosophila (Drosophila) carbonaria Patterson & ..., 1942 | Macartney rose |
| Drosophila (Drosophila) cardini Sturtevant, 1916 | Mexican buckeye |
| Drosophila (Drosophila) funebris Fabricius, 1787 | Large vinegar fly |
| Drosophila (Drosophila) hydei Sturtevant, 1921 | Horse chestnut |
| Drosophila (Drosophila) immigrans Sturtevant, 1921 | Horse chestnut |
| Drosophila (Drosophila) mercatorum Patterson & ..., 1942 | Macartney rose |
| Drosophila (Drosophila) montana Stone, Griff..., 1941 | |
| Drosophila (Drosophila) polychaeta Patterson & ..., 1942 | Macartney rose |
| Drosophila (Drosophila) repleta Wollaston, 1858 | False gilia |
| Drosophila (Drosophila) testacea (Roser, 1840) | ⇒ Drosophila testacens Wheeler, 1981 |
| Drosophila (Drosophila) transversa Fallen, 1823 | |
| Drosophila (Drosophila) virilis Sturtevant, 1916 | Mexican buckeye |
| Drosophila (Phloridosa) floricola (Sturtevant, 1942) | ⇒ Drosophila lutzii Sturtevant, 1916 |
| Drosophila (Sophophora) ananassae Doleschall, 1858 | Pomace fly |
| Drosophila (Sophophora) brevina Wheeler, 1981 | |
| Drosophila (Sophophora) brevis (Walker, 1852) | ⇒ Drosophila brevina Wheeler, 1981 |
| Drosophila (Sophophora) melanogaster (Meigen, 1830) | ⇒ Drosophila macquarti Wheeler, 1981 |
| Drosophila (Sophophora) populi Wheeler & Th..., 1961 | Strawberry groundcherry |
| Drosophila (Sophophora) pseudoobscura Frolova, 1929 | |
| Drosophila (Sophophora) simulans Sturtevant, 1919 | Apaac |
| Drosophila (Sophophora) willistoni Townsend, 1915 | Mexican buckeye |
| Drosophila acutilabella Stalker, 1953 | Remy's sandmat |
| Drosophila affinis Sturtevant, 1916 | |
| Drosophila alabamensis (Sturtevant, 1918) | ⇒ Hirtodrosophila alabamensis Sturtevant, 1918 |
| Drosophila albipes Walker, 1852 | |
| Drosophila algonquin Sturtevant &..., 1936 | Ceboruquillo |
| Drosophila americana Spencer, 1938 | |
| Drosophila arizonae Ruiz & Wasse..., 1990 | |
| Drosophila athabasca Sturtevant &..., 1936 | |
| Drosophila azteca Sturtevant &..., 1936 | Ceboruquillo |
| Drosophila basdeni (Wheeler, 1957) | ⇒ Lordiphosa basdeni Wheeler, 1957 |
| Drosophila bifurca Patterson & ..., 1942 | Macartney rose |
| Drosophila borealis Patterson, 1952 | |
| Drosophila brooksi (Pipkin, 1961) | ⇒ Scaptodrosophila brooksae Pipkin, 1961 |
| Drosophila buskii (Coquillett, 1901) | ⇒ Drosophila busckii Cocquillett, 1901 |
| Drosophila californica Sturtevant, 1923 | Buckeye |
| Drosophila carsoni Wheeler, 1957 | Missouri groundcherry |
| Drosophila chagrinensis (Stalker & Sp..., 1939) | ⇒ Hirtodrosophila chagrinensis Stalker & Sp..., 1939 |
| Drosophila cinerea (Patterson & ..., 1942) | ⇒ Hirtodrosophila cinerea Patterson & ..., 1942 |
| Drosophila colorata Walker, 1849 | Largeflower milkweed |
| Drosophila deflecta Malloch, 1924 | Smallflower bur cucumber |
| Drosophila duncani (Sturtevant, 1918) | ⇒ Hirtodrosophila duncani Sturtevant, 1918 |
| Drosophila euronotus Patterson & ..., 1952 | Smooth rose |
| Drosophila falleni Wheeler, 1960 | |
| Drosophila flavomontana Patterson, 1952 | |
| Drosophila flavopinicola Wheeler, 1954 | Clammy groundcherry |
| Drosophila fronto Walker, 1852 | |
| Drosophila fulvalineata Coquillett, 1898 | Macartney rose |
| Drosophila grisea (Patterson & ..., 1942) | ⇒ Hirtodrosophila grisea Patterson & ..., 1942 |
| Drosophila guttifera Walker, 1849 | Largeflower milkweed |
| Drosophila hamatofila Patterson & ..., 1942 | Macartney rose |
| Drosophila innubila Spencer, 1943 | Milk purslane |
| Drosophila lacicola Patterson, 1944 | Chinese rose |
| Drosophila latifasciaeformis (Duda, 1940) | ⇒ Scaptodrosophila latifasciaeformis Duda, 1940 |
| Drosophila lebanonensis (Wheeler, 1949) | ⇒ Scaptodrosophila lebanonensis Wheeler, 1949 |
| Drosophila linearis Walker, 1852 | |
| Drosophila longala (Patterson & ..., 1942) | ⇒ Hirtodrosophila longala Patterson & ..., 1942 |
| Drosophila longicornis Patterson & ..., 1942 | Macartney rose |
| Drosophila lowei Heed, Crumpa..., 1968 | Pygmy buttercup |
| Drosophila lutzii Sturtevant, 1916 | Mexican buckeye |
| Drosophila macquarti Wheeler, 1981 | |
| Drosophila macroptera Harris, 1841 | Macartney rose |
| Drosophila macrospina Stalker & Sp..., 1939 | Alpine sandmat |
| Drosophila magnaquinaria Wheeler, 1954 | Clammy groundcherry |
| Drosophila mainlandi Patterson, 1943 | |
| Drosophila melanica Sturtevant, 1916 | Mexican buckeye |
| Drosophila melanissima Sturtevant, 1916 | Mexican buckeye |
| Drosophila melanura Miller, 1944 | Pearshaped smelowskia |
| Drosophila meridiana Patterson & ..., 1942 | Macartney rose |
| Drosophila mettleri Heed, 1977 | Low spearwort |
| Drosophila micromelanica Patterson, 1941 | Dog rose |
| Drosophila minuta (Walker, 1852) | ⇒ Hirtodrosophila hirtominuta Bachli, 1974 |
| Drosophila miranda Townsend, 1916 | |
| Drosophila mojavensis Patterson & ..., 1940 | Virginia rose |
| Drosophila mulleri Sturtevant, 1921 | Horse chestnut |
| Drosophila munda Spencer, 1942 | Spreading sandmat |
| Drosophila narragansett Sturtevant &..., 1936 | Ceboruquillo |
| Drosophila nebulosa Sturtevant, 1916 | Mexican buckeye |
| Drosophila nigrohalterata (Duda, 1925) | ⇒ Hirtodrosophila nigrohalterata Duda, 1925 |
| Drosophila nigrohydei Patterson & ..., 1942 | Macartney rose |
| Drosophila nigromelanica Patterson & ..., 1942 | Macartney rose |
| Drosophila nigrospiracula Patterson & ..., 1942 | Macartney rose |
| Drosophila novamexicana Patterson, 1941 | |
| Drosophila novitskii Zetterstedt, 1859 | |
| Drosophila occidentalis Spencer, 1942 | Spreading sandmat |
| Drosophila orbospiracula (Patterson & ..., 1942) | ⇒ Hirtodrosophila orbospiracula Rohdendorf, 1937 |
| Drosophila ordinaria (Coquillett, 1904) | ⇒ Hirtodrosophila ordinaria Coquillett, 1904 |
| Drosophila pachea Patterson & ..., 1942 | Macartney rose |
| Drosophila palustris Spencer, 1942 | Spreading sandmat |
| Drosophila paramelanica Patterson, 1942 | |
| Drosophila peninsularis Patterson & ..., 1942 | Macartney rose |
| Drosophila persimilis Dobzhansky &..., 1944 | |
| Drosophila pictiventris (Duda, 1925) | ⇒ Hirtodrosophila pictiventris Duda, 1925 |
| Drosophila pinicola Sturtevant, 1942 | Bush's chestnut |
| Drosophila putrida Sturtevant, 1916 | Mexican buckeye |
| Drosophila quinaria Reinhard, 1967 | Scarlet globemallow |
| Drosophila recens Wheeler, 1960 | |
| Drosophila rellima Wheeler, 1960 | |
| Drosophila ritae Patterson & ..., 1942 | Macartney rose |
| Drosophila robusta Sturtevant, 1916 | Mexican buckeye |
| Drosophila rubrifrons Patterson & ..., 1942 | Macartney rose |
| Drosophila seminole Sturtevant &..., 1936 | Ceboruquillo |
| Drosophila sigmoides Loew, 1872 | Juniper globemallow |
| Drosophila stalkeri Wheeler, 1954 | Clammy groundcherry |
| Drosophila subfunebris Stalker & Sp..., 1939 | Alpine sandmat |
| Drosophila suboccidentalis Spencer, 1942 | Spreading sandmat |
| Drosophila subpalustris Spencer, 1942 | Spreading sandmat |
| Drosophila suffusca Spencer, 1943 | Milk purslane |
| Drosophila tenebrosa Spencer, 1943 | Milk purslane |
| Drosophila tenuipes Walker, 1849 | |
| Drosophila testacens Wheeler, 1981 | |
| Drosophila thoracis (Williston, 1896) | ⇒ Hirtodrosophila thoracis Williston, 1896 |
| Drosophila tripunctata (Loew, 1862) | ⇒ Drosophila immigrans Sturtevant, 1921 |
| Drosophila trispina Wheeler, 1949 | |
| Drosophila victoria (Sturtevant, 1942) | ⇒ Scaptodrosophila victoria Sturtevant, 1942 |
| Drosophila wheeleri Patterson & ..., 1952 | Japanese rose |
| Hirtodrosophila alabamensis Sturtevant, 1918 | |
| Hirtodrosophila chagrinensis Stalker & Sp..., 1939 | |
| Hirtodrosophila cinerea Patterson & ..., 1942 | |
| Hirtodrosophila duncani Sturtevant, 1918 | |
| Hirtodrosophila grisea Patterson & ..., 1942 | |
| Hirtodrosophila hirtominuta Bachli, 1974 | |
| Hirtodrosophila longala Patterson & ..., 1942 | |
| Hirtodrosophila nigrohalterata Duda, 1925 | |
| Hirtodrosophila orbospiracula Rohdendorf, 1937 | |
| Hirtodrosophila ordinaria Coquillett, 1904 | |
| Hirtodrosophila pictiventris Duda, 1925 | |
| Hirtodrosophila thoracis Williston, 1896 | |
| Lordiphosa basdeni Wheeler, 1957 | |
| Microdrosophila quadrata Sturtevant, 1916 | |
| Mycodrosophila claytonae Wheeler & Ta..., 1963 | |
| Mycodrosophila dimidiata Loew, 1862 | |
| Mycodrosophila stalkeri Wheeler & Ta..., 1963 | |
| Paramycodrosophila anomala Wheeler, 1954 | Clammy groundcherry |
| Paramycodrosophila centralis Wheeler, 1954 | Clammy groundcherry |
| Scaptodrosophila brooksae Pipkin, 1961 | |
| Scaptodrosophila latifasciaeformis Duda, 1940 | |
| Scaptodrosophila lebanonensis Wheeler, 1949 | |
| Scaptodrosophila victoria Sturtevant, 1942 | |
| Scaptomyza (Hemiscaptomyza) trochanterata Collin, 1953 | |
| Scaptomyza (Hemiscaptomyza) unipunctum Zetterstedt, 1847 | |
| Scaptomyza (Mesoscaptomyza) adusta Loew, 1862 | |
| Scaptomyza (Mesoscaptomyza) vittata Coquillett, 1895 | |
| Scaptomyza (Parascaptomyza) adusta Loew, 1862 | Native cabbage leaf miner |
| Scaptomyza (Parascaptomyza) pallida Zetterstedt, 1847 | Pomace Fly |
| Scaptomyza (Scaptomyza) flava Fallen, 1823 | Blind's bryum moss |
| Scaptomyza (Scaptomyza) graminum Fallen, 1823 | Imported cabbage leaf miner |
| Scaptomyza (Scaptomyza) montana (Wheeler, 1949) | ⇒ Scaptomyza flava Fallen, 1823 |
| Scaptomyza (Scaptomyza) teinoptera Hackman, 1955 | |
| Scaptomyza apicata Thomson, 1869 | |
| Scaptomyza bipunctipennis Wheeler, 1952 | Ivyleaf groundcherry |
| Scaptomyza flaviventris Hackman, 1959 | |
| Scaptomyza hirsuta Wheeler, 1949 | |
| Scaptomyza hsui Hackman, 1955 | |
| Scaptomyza maculifera Becker, 1919 | |
| Scaptomyza malada Wheeler & Ta..., 1966 | Groundcherry |
| Scaptomyza nigrita Wheeler, 1952 | Ivyleaf groundcherry |
| Scaptomyza paradusta Wheeler, 1952 | Ivyleaf groundcherry |
| Scaptomyza paravittata Wheeler, 1952 | Ivyleaf groundcherry |
| Scaptomyza terminalis Loew, 1863 | |
| Scaptomyza wheeleri Hackman, 1959 | |
