| Melanagromyza achilleana Sehgal, 1971 | Long-tube evening primrose |
| Melanagromyza actaeae Sehgal, 1971 | Long-tube evening primrose |
| Melanagromyza alaskae Spencer, 1969 | Giant spurge |
| Melanagromyza angelicae Frost, 1934 | |
| Melanagromyza bidenticola Sehgal, 1971 | Long-tube evening primrose |
| Melanagromyza bidentis Spencer, 1966 | Rattlesnake weed |
| Melanagromyza buccalis Spencer, 1969 | Giant spurge |
| Melanagromyza burgessi Malloch, 1913 | |
| Melanagromyza caerulea Malloch, 1913 | Leafminer fly |
| Melanagromyza caribbea Spencer, 1973 | |
| Melanagromyza chaptaliae Spencer, 1973 | Rattlesnake weed |
| Melanagromyza chillcotti Spencer, 1986 | Alkali sandmat |
| Melanagromyza chillcottiana Spencer, 1986 | Alkali sandmat |
| Melanagromyza cirsiophila Spencer, 1981 | Candelilla |
| Melanagromyza corralensis Spencer, 1981 | Candelilla |
| Melanagromyza diantherae Malloch, 1921 | |
| Melanagromyza erechtitidis Spencer, 1973 | Rattlesnake weed |
| Melanagromyza fastosa (Spencer, 1969) | ⇒ Ophiomyia fastosa Spencer, 1969 |
| Melanagromyza floridensis Spencer, 1963 | Abrams' sandmat |
| Melanagromyza floris Spencer, 1963 | Abrams' sandmat |
| Melanagromyza gibsoni Malloch, 1915 | |
| Melanagromyza gnaphalii Spencer, 1981 | Candelilla |
| Melanagromyza gynurae Spencer, 1959 | |
| Melanagromyza heliotropii Spencer, 1973 | |
| Melanagromyza inornata Spencer, 1969 | Giant spurge |
| Melanagromyza laetifica Spencer, 1969 | Giant spurge |
| Melanagromyza longensis Spencer, 1986 | Alkali sandmat |
| Melanagromyza malefica (Spencer, 1981) | ⇒ Melanagromyza burgessi Malloch, 1913 |
| Melanagromyza malevola Spencer, 1981 | Candelilla |
| Melanagromyza maligna Spencer, 1981 | Candelilla |
| Melanagromyza marellii Brèthes, 1920 | |
| Melanagromyza marinensis Spencer, 1981 | Candelilla |
| Melanagromyza martini Spencer, 1969 | Giant spurge |
| Melanagromyza matricarioides Spencer, 1969 | Giant spurge |
| Melanagromyza miamensis Spencer, 1973 | |
| Melanagromyza minima Malloch, 1913 | |
| Melanagromyza minimoides Spencer, 1966 | Rattlesnake weed |
| Melanagromyza miranda Spencer, 1969 | Giant spurge |
| Melanagromyza modesta Spencer, 1969 | Giant spurge |
| Melanagromyza mugensis Spencer, 1981 | |
| Melanagromyza muguensis (Spencer, 1981) | ⇒ Melanagromyza mugensis Spencer, 1981 |
| Melanagromyza occidentalis Spencer, 1969 | Giant spurge |
| Melanagromyza osoflacensis Spencer, 1981 | Candelilla |
| Melanagromyza palaensis Spencer, 1981 | Candelilla |
| Melanagromyza proboscidata Spencer, 1986 | Alkali sandmat |
| Melanagromyza quadrisetosa Spencer, 1981 | Candelilla |
| Melanagromyza radicicola (Steyskal, 1981) | ⇒ Melanagromyza minimoides Spencer, 1966 |
| Melanagromyza riparella Hendel, 1923 | |
| Melanagromyza ruelliae Spencer, 1966 | Rattlesnake weed |
| Melanagromyza sagehenensis Spencer, 1981 | Candelilla |
| Melanagromyza scrophulariae Spencer, 1981 | Candelilla |
| Melanagromyza setifrons Melander, 1913 | |
| Melanagromyza shewelli Spencer, 1969 | |
| Melanagromyza splendida Frick, 1953 | Leafminer fly |
| Melanagromyza subvirens Malloch, 1915 | |
| Melanagromyza tamia Melander, 1913 | |
| Melanagromyza tetrica Spencer, 1969 | Giant spurge |
| Melanagromyza trispinella Spencer, 1981 | Candelilla |
| Melanagromyza trispinosa Spencer, 1981 | Candelilla |
| Melanagromyza ultima Spencer, 1986 | Alkali sandmat |
| Melanagromyza urticella Spencer, 1981 | Candelilla |
| Melanagromyza vectabilis Spencer, 1973 | |
| Melanagromyza verbesinae Spencer, 1986 | Alkali sandmat |
| Melanagromyza virens Loew, 1869 | |
| Melanagromyza virginiensis Spencer, 1986 | Alkali sandmat |
| Melanagromyza viridis (Frost, 1931) | ⇒ Melanagromyza gynurae Spencer, 1959 |
| Melanagromyza walleyi Spencer, 1986 | Alkali sandmat |
| Melanagromyza wedeliae Spencer, 1973 | |
| Ophiomyia abutilivora Spencer, 1986 | Alkali sandmat |
| Ophiomyia ambrosia Spencer, 1981 | Candelilla |
| Ophiomyia apta Spencer, 1981 | Candelilla |
| Ophiomyia arizonensis Spencer, 1986 | Alkali sandmat |
| Ophiomyia asterovora Spencer, 1969 | Giant spurge |
| Ophiomyia asymmetrica Spencer, 1986 | Alkali sandmat |
| Ophiomyia banffensis Spencer, 1969 | Giant spurge |
| Ophiomyia bernardinensis Spencer, 1981 | Candelilla |
| Ophiomyia boulderensis Spencer, 1986 | Alkali sandmat |
| Ophiomyia camarae Spencer, 1963 | Abrams' sandmat |
| Ophiomyia carolinae Spencer, 1986 | Alkali sandmat |
| Ophiomyia carolinensis Spencer, 1986 | Alkali sandmat |
| Ophiomyia chondrillae Spencer, 1986 | Alkali sandmat |
| Ophiomyia commendata Spencer, 1981 | Candelilla |
| Ophiomyia congregata Malloch, 1913 | |
| Ophiomyia coniceps Malloch, 1915 | |
| Ophiomyia debilis Spencer, 1981 | Candelilla |
| Ophiomyia definita (Spencer, 1981) | ⇒ Ophiomyia subdefinita Spencer, 1986 |
| Ophiomyia delecta Spencer, 1981 | Candelilla |
| Ophiomyia devia Spencer, 1981 | Candelilla |
| Ophiomyia duodecima Spencer, 1969 | Giant spurge |
| Ophiomyia eldorensis Spencer, 1986 | Alkali sandmat |
| Ophiomyia fastella Spencer, 1981 | Candelilla |
| Ophiomyia fastosa Spencer, 1969 | |
| Ophiomyia fida Spencer, 1982 | Candelilla |
| Ophiomyia frosti Spencer, 1986 | Alkali sandmat |
| Ophiomyia gentilis Spencer, 1973 | |
| Ophiomyia haydeni Spencer, 1973 | |
| Ophiomyia jacintensis Spencer, 1981 | Candelilla |
| Ophiomyia kingsmerensis Spencer, 1969 | Giant spurge |
| Ophiomyia labiatarum Hering, 1937 | Blooddrops |
| Ophiomyia lacertosa Spencer, 1973 | |
| Ophiomyia lantanae Froggat, 1919 | Lantana seed fly |
| Ophiomyia lassa Spencer, 1981 | Candelilla |
| Ophiomyia lauta Spencer, 1969 | |
| Ophiomyia levata Spencer, 1981 | Candelilla |
| Ophiomyia lippiae Spencer, 1966 | Rattlesnake weed |
| Ophiomyia maculata Spencer, 1981 | Candelilla |
| Ophiomyia malitiosa Spencer, 1981 | Candelilla |
| Ophiomyia maura Meigen, 1838 | |
| Ophiomyia melica Spencer, 1981 | Candelilla |
| Ophiomyia monticola Sehgal, 1968 | Engelmann's evening primrose |
| Ophiomyia nasuta Melander, 1913 | |
| Ophiomyia nona Spencer, 1969 | Giant spurge |
| Ophiomyia obstipa Spencer, 1973 | |
| Ophiomyia octava Spencer, 1969 | Giant spurge |
| Ophiomyia parva Spencer, 1986 | Alkali sandmat |
| Ophiomyia parvella Spencer, 1973 | |
| Ophiomyia praecisa Spencer, 1969 | Giant spurge |
| Ophiomyia prima Spencer, 1969 | Giant spurge |
| Ophiomyia proboscidea Strobl, 1900 | |
| Ophiomyia pulicaria Meigen, 1830 | |
| Ophiomyia quarta Spencer, 1969 | Giant spurge |
| Ophiomyia quinta Spencer, 1969 | Giant spurge |
| Ophiomyia secunda Spencer, 1969 | Giant spurge |
| Ophiomyia septima Spencer, 1969 | Giant spurge |
| Ophiomyia sexta Spencer, 1969 | Giant spurge |
| Ophiomyia shastensis Spencer, 1981 | Candelilla |
| Ophiomyia similata Malloch, 1918 | |
| Ophiomyia simplex Loew, 1869 | Asparagus miner |
| Ophiomyia stricklandi Sehgal, 1971 | Long-tube evening primrose |
| Ophiomyia subdefinita Spencer, 1986 | Alkali sandmat |
| Ophiomyia subpraecisa Spencer, 1986 | Alkali sandmat |
| Ophiomyia tertia Spencer, 1969 | Giant spurge |
| Ophiomyia texana Malloch, 1913 | |
| Ophiomyia texella Spencer, 1986 | Alkali sandmat |
| Ophiomyia tiliae Couden, 1908 | |
| Ophiomyia undecima Spencer, 1969 | Giant spurge |
| Ophiomyia vibrissata Malloch, 1913 | |
| Ophiomyia virginiensis Spencer, 1986 | Alkali sandmat |
| Ophiomyia vockerothi Spencer, 1986 | Alkali sandmat |
| Ophiomyia wabamunensis Spencer, 1969 | Giant spurge |
| Ophiomyia yolensis Spencer, 1981 | Candelilla |
